The effect of Estrogen and Imipramine therapy on the strees urinary incontinence (SUI) in menopaused women

Background: Women spend more than One – third of their life in postmenstrual period and more than 50% of them have urogenital problems in this period. The most common type of urinary incontinence in women is stress urinary incontinence and middle aged women are the most affected persons. Materials and methods: We treated 93 menopaused women during 3 months. There were three groups and each group contained 31 patients. First group took Estrogen, the second group used Imipramine and the third group used estrogen in combination with Impramine. This study was a clinical trial and its main aim was verification of Estrogen effects on the treatment of stress urinary incontinence compared with Imipramine in menopaused women. We obtained information by using a questionnaire. Results: The improvement percent of first group was 22.5% (7 patients). Improvement percent of second group was 54.8% (17 patients) and in last group was 70.9% (22 patients). Conclusion: Imipramine is more effective than Estrogen in treatment of stress urinary incontinence and combination therapy with these two drugs is not more effective than Imipramine alone.